Number Strings Paths

Approach

From the digit before the -, you have a corner of key square to start at:

1 = top left, 2 = top right, 3 = bottom right, 4 = bottom left

Use the number string to move along the streets:

1 = N; 1.5 = NE; 2 = E; 2.5 = SE; 3 = S; 3.5 = SW; 4 = W

When you reach the end, take the nth letter of its name, where n is the number after the - at the end of the string.

Solution

The complete set of destination letters identified by the method above is (by consensus):

FRBPULAFHPOSMLUCNIDYMENDBKIELGTPDOAAKILTIO

NOTE: Chimera245 disagrees with this, for the reasons in the table below, his answer being:

FRBVULANHPOSMLUCNIDYMENDBKIELGTPDOAAKILTIO

Card	String	Path	Destination	Letter	Consensus
#029+	1-14443432.5-3	Clavus Free Flow Shone Schloss Shiran	Reflex	F
#058+	2-21122214-4	Schloss The Shift Dalia Horizon	Myers	R
#029-	3-232.52.51.5-1	Polis The Shift Phillips	Barnard	B
#058-	4-23232.534334-1	Polis Teichman Ascent Sharp Acute The Shift Milamont Sidney	Van Den Huygens	V [was P]
#040-	1-1144144414432.5-4	Clavus Dalia Perdido Leigh Osiris Bell Magine	Obtuse	U
#040+	2-11444414412-3	Sidney Dalia Skogstrom Leigh Shone	Bell	L
#063+	3-34-1	Sidney	Ascent	A
#060-	4-44444444111111111114-3	Polis Magine	Jennings (Holl,Schloss,Free,Dalia,Leigh Obtuse,Bell,Pullman,Open,Reflex,Jennions)	N (was F)
#060+	1-414141414144144441-1			H
#063-	2-414441141-1			P
#090-	3-433333334-2			O
#090+	4-4444444443.5-1			S
#094+	1-1114112321-1			M
#094-	2-4111111441-2			L
#096-	3-44411414441444112.5-4			U	?
#136-	4-143334-3			C
#096+	1-222233332-4			N
#188-	2-21121111221-4			I	?
#136+	3-2333234-1			D
#188+	4-11122221412234-2			Y
#191-	1-344411444443-1			M
#191+	2-11444444444411111111444-2			E
#192+	3-3333322333332-4			N
#203+	4-33223333234-4			D
#192-	1-444444114411112-1			B
#218+	2-4444433333323-2			K
#203-	3-11144144144443-3			I
#222+	4-1414411122-2			E
#218-	1-44334-3			L
#156+	2-111221111112-4			G
#222-	3-34433333432-4			T
#235-	4-222233332222.5-1			P	?
#235+	1-4444444434444444444443-4			D
#237-	2-1222323-2			O
#236-	3-2112223-2			A
#236+	4-4333223323-3			A
#250-	1-343-2			K
#156-	2-2232-4			I
#237+	3-3333334433334-1			L
#250+	4-3322333333333332-1			T
#253+	1-1111211112-4			I
#253-	2-111114441114114-1			O

Raw Data

Card	Upright Number	Reversed Number	End location (PXC)	Notes
Season 1 Card #029 - Beware the Puzzle Monsters	1-14443432.5-3	3-232.52.51.5-1	pos Reflex Way, F	Card also contains playing card symbol.
Season 1 Card #040 - Baby On Board	2-11444414412-3	1-1144144414432.5-4	pos Belle Avenue, 3rd, L
Season 1 Card #058 - Breaking And Entering	2-21122214-4 ENNEEENW	4-23232.534334-1	pos Myers Avenue, 4th, R neg Polygon Approach, 1st, P
Season 1 Card #060 - Celebration	1-414141414144144441-1	4-44444444111111111114-3	pos Reflex, 1st, R
Season 1 Card #063 - The Next Generation	3-34-1	2-414441141-1	pos Ascent Lane, 1st, A
Season 1 Card #090 - Also Known As	4-4444444443.5-1 WWWWWWWWW(SW)	3-433333334-2	pos Stephenson Road, 1st, S
Season 1 Card #094 - Prime Rhyme Crime	2-4111111441-2	1-1114112321-1		Numbers are vertical.
Season 1 Card #096 - Castle in The Sky	1-222233332-4	3-44411414441444112.5-4
Season 1 Card #136 - Bling Bunny	3-2333234-1 ESSSESW	4-143334-3	pos Descent Road, 1st, D	Numbers are vertical.
Season 1 Card #156 - Going Dotty	2-111221111112-4	2-2232-4		Numbers are vertical. This card has writing revealed under a black light. See below.
Season 1 Card #188 - Hybridization	4-11122221412234-2	2-21121111221-4		Numbers are across from each other in one line.
Season 1 Card #191 - My Dear Watson	2-11444444444411111111444-2	1-344411444443-1
Season 1 Card #192 - Pronunciation	3-3333322333332-4	1-444444114411112-1
Season 1 Card #203 - Ecliptic	4-33223333234-4	3-11144144144443-3		Numbers are vertical.
Season 1 Card #218 - The World	2-4444433333323-2	1-44334-3 WWSSW	neg Holl Lane, 3rd, L
Season 1 Card #222 - Instigator	4-1414411122-2	3-34433333432-4		Numbers are vertical.
Season 1 Card #235 - Circuitous	1-4444444434444444444443-4	4-222233332222.5-1
Season 1 Card #236 - Swarms	4-4333223323-3	3-2112223-2
Season 1 Card #237 - Roaming Identity	3-3333334433334-1	2-1222323-2		Numbers are vertical. This card has micro-printing on it: "otpaaworldtdnia 1.56.29".
Season 1 Card #250 - Manoeuvers	4-3322333333333332-1	1-343-2		The number string 1-343-2 is in a bold font.
Season 1 Card #253 - Sightseeing	1-1111211112-4	2-111114441114114-1	pos, Meridian, 4th, I neg Peroido, 1st, P OR Camelia Lane, C