Ceretin
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Advertisements for Ceretin appear througout the content of the Perplex City Sentinel, associated with the slogans, "problems untangled", "stay sharp," and "faster, sharper and more alert."
The ads resemble pharmaceutical company advertisements and presumably Ceretin is some kind of cognitive treatment or medication.
Potential relationship
According to the Sentinel article "Cube Stolen in Deadly Raid" by Iona Rodie, Fran Mendling was killed using a "neuro-suppressant device."